Which Would You Choose

If you could take a drug which made you happy, in a way you've never felt or thought before, let alone was something you could ever achieve, and you had to take it every day to be happy, but that drug also made you physically sick, sick enough to make life miserable for short periods of time, made you angry about yourself and with yourself for taking it, and made you more depressed than when you didn't take it, would you still take it?